Tert-Butylhydroquinone is an aromatic organic compound.It is a derivative of hydroquinone, substituted with tert-butyl group.A review of scientific literature concerning the toxicity of TBHQ determined that there is a wide margin of safety between the levels of intake by humans and the doses that produce adverse effects in animal studies.
Antioxidant is a substance added in small quantities to hydrocarbons which are susceptible to oxidation, such as rubbers, plastics, foods, and oils to inhibit or slow oxidative processes, while being itself oxidized.Tert-butylhydroquinone (TBHQ) is a white, crystalline solid having a characteristic odor. It is practically insoluble in water but soluble in alcohol and in ether. TBHQ is a general purpose antioxidant used to preserve various oils, fats and food items by retarding their oxidative deterioration.
TBHQ is a highly effective antioxidant.As a food additives, its E number is E319. It is added to a wide range of foods, with the highest limit (1000 mg/kg) permitted for frozen fish and fish products.In perfumery, it is used as a fixative to lower the evaporation rate and improve stability. It is also added to varnishes, lacquers, resins, and oil field additives.Both the European Food Safety Authority.Other studies, however, have shown opposite effects including inhibition against HCA-induced carcinogenesis.
TBHQ is an antioxidant widely used in foods, cosmetics and rubbers, especially in oils and fats.We developed a simple purification method for it.[3]But it has not been used widely, and can not be sold very well.TBHQ could be produced with 60% yield from DTBHQ catalyzed by p-toluenesulfonic acid (PTSA).
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