Glycine is a colourless, sweet-tasting crystalline solid. Glycine was discovered in 1820, by Henri Braconnot who boiled gelatin with sulfuric acid. There are two producers of glycine in the United States. Chattem Chemicals, Inc., purchased by Sun Pharmaceutical. Glycine exists in zwitterionic form in solution.
Glycine encephalopathy, which is also known as nonketotic hyperglycinemia or NKH, is a genetic disorder characterized by abnormally high levels of a molecule called glycine. Researchers have identified several other types of glycine encephalopathy with variable signs and symptoms. The most common of these atypical types is called the infantile form. These cases are classified as transient glycine encephalopathy. In this form of the condition, glycine levels decrease to normal or near-normal after being very high at birth.
Glycine is one of the non-essential amino acids and is used to help create muscle tissue and convert glucose into energy. Glycine is used in the body to help construct normal DNA and RNA strandshe genetic material needed for proper cellular function and formation. Glycine is essential for a healthy, normally functioning digestive system. Glycine as a food additive that is necessary for central nervous system function.
This condition is inherited in an autosomal recessive pattern, which means both copies of the gene in each cell have mutations. The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition. Affected infants experience a progressive lack of energy, feeding difficulties, weak muscle tone, abnormal jerking movements, and life-threatening problems with breathing.
Others: Inositol L-Arginine HCL
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