Sunday, February 19, 2012

Adverse reactions of Caffeine Anhydrous

Adverse reactions of Caffeine Anhydrous
(1) caffeinated drinks occasionally taking too much can cause nausea, headaches or insomnia. Long-term habit of too much to take, there may be headache, nervousness, agitation and anxiety.
(2) adult lethal dose is generally 10g, the blood concentration of 60-160μgml, tubular or red blood cells in urine, reported died of hepatic coma.
Cardiovascular system: reported Computer users eat more flaxseed oil that women every day to drink six or more cups of coffee, and 2.5 times higher risk of myocardial infarction. Caffeine can cause atrioventricular node effective refractory period shortened, causing the tachyarrhythmia and premature.
Nervous system, caffeine can cause anxiety, food additives insomnia, nervousness, and tremor; large doses can produce anxiety neurosis-like, such as irritability, insomnia, palpitations, flushing, and headache.
Digestive:large doses of caffeine can cause nausea and vomiting. Caffeine is a strong stimulant of gastric acid secretion, allows duodenal ulcer aggravated.
Endocrine, metabolic: coffee or equivalent caffeine intramuscular injection, so that increase in free fatty acids in the blood, elevated blood glucose, and catecholamines increased.
Skin: reported urticaria.
Contraindications
Patients with gastric ulcer disabled.
Myocardium susceptible to irritation of the patients, caffeine can cause arrhythmia, should be limited to the application. Application of caffeine treatment, the babies, high incidence of gastroesophageal reflux.
Drug Interactions
(1) isoniazid and tensiomin, urethane can induce caffeine to improve efficiency, increase the concentration in the latter brain tissue, liver and renal Citric acid anhydrous concentrations declined.
(2) oral contraceptives may slow caffeine clearance.
Caffeine can change the blood levels of antipsychotics.
Drug overdose
Over the amount of signs: irritability, disturbance, tinnitus, vertigo and blind spots or flashing light, muscle tremors, increased heart rate and premature beats. Continuous application of large doses can cause poisoning, the performance of the behavior and mental physiological symptoms, such as unease, anxiety, irritability, excitement, muscle tremors, sleep disturbances, headache, sensory disturbances, cardiac, and gastrointestinal symptoms, a large dose or even epileptiform convulsions.

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