Chondroitin sulfate is a chemical that is normally found in cartilage around joints in the body. Chondroitin sulfate is manufactured from animal sources such as cow cartilage. Chondroitin sulfate is often sold in combination products that also contain glucosamine sulfate. Buying a combination product is probably not worth any extra cost. Chondroitin sulfate is a component of human connective tissues found in cartilage and bone.
A study of 300 people with knee osteoarthritis who received either chondroitin alone or placebo showed that chondroitin may slow progression of knee OA. Chondroitin taken with blood-thinning medication like NSAIDs may increase the risk of bleeding. If you are allergic to sulfonamides, start with a low dose of chondroitin sulfate and watch for any side effects. Presently, it is thought that unlike many medications available to treat arthritis pain and inflammation, glucosamine and chondroitin sulfate supplements have very few side effects.
We randomly assigned 1583 patients with symptomatic knee osteoarthritis to receive 1500 mg of glucosamine daily, 1200 mg of chondroitin sulfate as a food additives daily, both glucosamine and chondroitin sulfate, 200 mg of celecoxib daily, or placebo for 24 weeks. The rate of response in the celecoxib control group was 10.0 percentage points higher than that in the placebo control group (P=0.008). Glucosamine and chondroitin sulfate alone or in combination did not reduce pain effectively in the overall group of patients with osteoarthritis of the knee.
Chondroitin sulfate is a glycosaminoglycan (GAG) - also known as a mucopolysaccharide - a type of compound that binds to collagen and elastin in the formation of cartilage. Chondroitin sulfate is a biological polymer derived from connective tissue and supports cartilage production.
Other food additives: Xanthan Gum Ginseng Extract
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